Product ID:CYTOSAR-U STERILE POWDER
MSDS Date:06/30/1994
FSC:6505
NIIN:01-077-5690
MSDS Number: BWKXQ

Emergency Phone: 616-323-5122 (24 HOURS)

Info Phone: 30 PM)

Cage: 93703

Telephone: 616-833-5122/616-833-7555

Cage: 93703

CYTARABINE *94-4*

CAS: 147-94-4

RTECS: HA5425000

Fraction By Weight: <100%

OSHA PEL 2 UG/CUM

ACGIH TLV: 2 UG/CUM

LD50 LC50 Mixture:LD50 (ORAL, RAT) > 3,000 MG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:REPEATED OR CONTINUOUUS EYE OR SKIN
CONTACT MAY CAUSE IRRITATION. WHEN ADMINISTERED CLINICALLY BY
INTRAVENOUS INFUSION, ANOREXIA, NAUSEA, VOMITING OR DIARRHEA MAY
OCCUR. MAY CAUSE BONE MARROW SUPPRESS ION AND LOSS OF IMMUNE
RESPONSE, RESULTING IN POTENTIAL FOR PROLONGED BLEEDING AND
INFECTIONS.
Explanation of Carcinogenicity:THIS COMPOUND CONTAINS NO INGREDIENTS AT
CONCENTRATIONS OF 0.1% OR GREATER THAT ARE CARCINOGENS OR SUSPECT
CARCINOGENS.
Effects of Overexposure:NAUSEA, VOMITING, DIARRHEA, ANOREXIA, EYE
IRRITATION, SKIN IRRITATION, LOSS OF IMMUNE RESPONSE, PROLONGED
BLEEDING, SUSCEPTIBILITY TO INFECTIONS.
Medical Cond Aggravated by Exposure:CONTRAINDICATED IN PEOPLE WITH A
HISTORY OF HYPERSENSITIVITY TO CYTARABINE.

First Aid:GET MEDICAL ATTENTION IF SYMPTOMS PERSIST. EYE:FLUSH WITH
WATER FOR 15 MINUTES. HOLD EYELIDS OPEN. SKIN:WASH WITH SOAP &
WATER. INHALED:REMOVE TO FRESH AIR. ORAL:CONTACT A PHYSICIAN OR
POISON CONTROL CENTER.

Flash Point:NONFLAMMABLE
Lower Limits:NOT GIVEN
Upper Limits:NOT GIVEN
Extinguishing Media:WATER, ALCOHOL FOAM, CARBON DIOXIDE OR DRY
CHEMICAL.
Fire Fighting Procedures:WEAR PROTECTIVE CLOTHING AND NIOSH-APPROVED
SELF-CONTAINED BREATHING APPARATUS.
Unusual Fire/Explosion Hazard:AS WITH ALL FINELY DIVIDED ORGANIC
POWDERS, IT IS ADVISABLE TO ELIMINATE EXPLOSION HAZARDS BY METHODS
SUCH AS GROUNDING, INERTING ATMOSPHERE, CONTROLLING DUST.

Spill Release Procedures:REMOVE IGNITION SOURCES. CONTROL GENERATION OF
DUST/VAPORS. PROVIDE VENTILATION AND PERSONAL PROTECTIVE EQUIPMENT.
KEEP OUT OF DRAINS AND WATERRWAYS. VACUUM WITH HEPA-FILTERED AND
EXPLOSION-PROOF EQU IPMENT OR SCOOP SPILLED MATERIAL INTO
CONTAINERS.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:STORE IN COOL, DRY PLACE AWAY FROM
LIGHT. KEEP OUT OF REACH OF CHILDREN. LAUNDER CONTAMINATED CLOTHING
BEFORE REUSE.
Other Precautions:AVOID CONTACT WITH EYES, CLOTHING AND SKIN. WASH
THOROUGHLY AFTER HANDLING MATERIAL.

Respiratory Protection:APPROVED RESPIRATOR IF THERE IS OPPORTUNITY FOR
SPLASH, MIST OR AEROSOL GENERATION, ESPECIALLY IN LARGE QUANTITIES.
Ventilation:LOCAL EXHAUST
Protective Gloves:RUBBER.
Eye Protection:SAFETY GLASSES WITH SIDE SHIELDS.
Other Protective Equipment:EYE WASH STATION, PROTECTIVE CLOTHING FOR
EXPOSED AREAS OF SKIN.
Work Hygienic Practices:OBSERVE GOOD PERSONAL HYGIENE PRACTICES AND
RECOMMENDED PROCEDURES.
Supplemental Safety and Health
NONE SPECIFIED BY MANUFACTURER.

HCC:K2
Boiling Pt:B.P. Text:NOT GIVEN
Melt/Freeze Pt:M.P/F.P Text:NOT GIVEN
Decomp Temp:Decomp Text:NOT GIVEN
Vapor Pres:NOT GIVEN
Vapor Density:NOT GIVEN
Spec Gravity:NOT GIVEN
Evaporation Rate & Reference:NOT RELEVANT
Solubility in Water:FREELY SOLUBLE
Appearance and Odor:WHITE TO OFF-WHITE CRYSTALLINE POWDER

Stability Indicator/Materials to Avoid:YES
NONE SPECIFIED BY MANUFACTURER.
Stability Condition to Avoid:NONE SPECIFIED BY MANUFACTURER.
Hazardous Decomposition Products:CARBON DIOXIDE, CARBON MONOXIDE,
NITROGEN OXIDES.

Waste Disposal Methods:DISPOSE OF IN ACCORDANCE WITH ALL LOCAL, STATE
AND FEDERAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.